Many important processes in cell and developmental biology are controlled by the spatial distribution of proteins. For example, highly non-uniform concentration of proteins can help the cell to be polarized. It is interesting to note that on the distribution of proteins. 1) In the first part , we discuss about the minimum model of cell polarization to capture the role of geometry. Here, we show that the geometry can bring robustness in the steady-state distribution of proteins. 2) In the second part, we discuss about role of geometry on non-conserved mass models in reaction-diffusion systems. Here, we show that the non-conserved mass models can show different behaviour in response to geometry compared to minimum model for cell polarization.