Centre for Artificial Learning and Intelligence for Biological Research and Education (CALIBRE)

The Centre for Artificial Learning and Intelligence for Biological Research and Education (CALIBRE) was established jointly by ICTS and NCBS to advance interdisciplinary research at the interface of Artificial Intelligence and Biology. The centre is supported through a generous contribution from Mr. Vishal Gupta, founder of Reed India Consulting LLP, and Major Deepshikha Gupta.

CALIBRE aims to build a national hub for AI-driven biological research and education by leveraging the complementary expertise of ICTS and NCBS in theoretical sciences, computational methods, and biological systems.

The centre focuses on both “AI for Biology” and “Biology for AI.” This includes the development of AI tools for biological research, the use of machine learning in areas such as ecology, neuroscience, and public health, and the exploration of biologically inspired approaches to next-generation AI systems.


About Members Events Opportunities Publications Blogs Contact

  • Kumar, N. D., Shelley, M. J., & Chakrabarti, B. (2026). Growing, buckling, and swirling: Motility from polymerization. arXiv. https://arxiv.org/abs/2607.10446
  • Alsous, J. I., Chakrabarti, B., Palmer, B., & Shelley, M. J. (2026). The physical consequences of sperm gigantism. Nature Physics. https://doi.org/10.1038/s41567-026-03305-4
  • Ghosh, D., Chakrabarti, B., & Cheng, X. (2026). Density-controlled reversal of collective migration in bacterial aerotaxis. Physical Review Research, 8(3), 033059. https://doi.org/10.1103/y7l1-288v
  • Wang, Z., Grilli, J., Goyal, A., & Maslov, S. (2025). Resource ratio fluctuations drive the evolution of microbial metabolic strategies. bioRxiv. https://doi.org/10.64898/2025.12.18.695187
  • Feng, Z., Blumenthal, E., Mehta, P., & Goyal, A. (2025). A theory of ecological invasions and its implications for eco-evolutionary dynamics. Proceedings of the National Academy of Sciences, 122(49), e2505850122. https://doi.org/10.1073/pnas.2505850122
  • Ramachandran, R., & Goyal, A. (2026). Energy flow controls the stability of multitrophic ecosystems with stratified nonreciprocity. arXiv. https://arxiv.org/abs/2601.12717
  • Bauer, M., Goyal, A., Goyal, S., Reddy, G., Chakrabarti, S., Desai, M. M., Gilpin, W., Grilli, J., Husain, K., Jain, S., Jolly, M. K., Kawaguchi, K., Koseska, A., Lin, M., Narlikar, L., Pigolotti, S., Raju, A., Shrinivas, K., Siddharthan, R., ... Vaikuntanathan, S. (2026). Unifying theories in high-dimensional biophysics: Approaches, challenges and opportunities. npj Systems Biology and Applications, 12, 43. https://doi.org/10.1038/s41540-026-00680-9
  • Venkatanarayanan, N. N., & Goyal, A. (2026). Diverse communities promote the coexistence of closely related strains through emergent equalization and stabilization. arXiv. https://arxiv.org/abs/2603.15052
  • Li, S. Y., Feng, Z., Goyal, A., & Mehta, P. (2026). Emergent frequency-dependent selection predicts mutation outcomes in complex ecological communities. bioRxiv. https://doi.org/10.64898/2026.04.13.718251
  • Dal Bello, M., Liu, Y., Goyal, A., & Gore, J. (2026). Nutrient availability shapes the diversity and structure of microbial communities. bioRxiv. https://doi.org/10.64898/2026.04.14.718562
  • Wang, Z., Fu, Y., Goyal, A., & Maslov, S. (2026). Fitness advantage of sequential metabolic strategies emerges from community interactions in strongly fluctuating environments. PLOS Computational Biology, 22(5), e1014277. https://doi.org/10.1371/journal.pcbi.1014277
  • Rowland-Chandler, J., Shou, W., & Goyal, A. (2025). Resource diversity begets stability in complex ecosystems. bioRxiv. https://doi.org/10.1101/2025.10.20.683391
  • Burra, R., Sundarakumar, J. S., Malo, P. K., Pradhan, H., Prasad, R., Rai, P., Issac, T. G., Athreya, S., Sundaresan, R., et al. (2025). A unified measure for cognitive reserve that transcends rural and urban populations: Insights from two aging cohorts in southern India. Alzheimer's & Dementia, 21(Suppl. 6), e106281.
  • Athreya, S., Ishtiaq, F., Khandelwal, T., Pattabiraman, C., Rao, L., Sundaresan, R., & Thattaramppilly, R. M. (2026). Localized wastewater surveillance showed correlation but no early warning during Bengaluru's Omicron wave. PLOS Global Public Health, 6(4), e0004684.
  • Burra, R., Malo, P. K., Pradhan, H., Prasad, R., Rai, P., Issac, T. G., Sundarakumar, J. S., Athreya, S., & Sundaresan, R. (2026). Cognitive reserve in rural and urban populations: Insights from two aging cohorts in southern India. Alzheimer's Research & Therapy, 18, 121.
  • Eisen, A. J., Ostrow, M., Chandra, S., Kozachkov, L., Miller, E. K., & Fiete, I. R. (2025). Characterizing control between interacting subsystems with deep Jacobian estimation. Advances in Neural Information Processing Systems, 38, 51361–51406. https://proceedings.neurips.cc/paper_files/paper/2025/file/49c2ded2a18b0c0150dc1d7b6530943e-Paper-Conference.pdf

 


Institutions, Leadership & Donors
Host Institutions

International Centre for Theoretical Sciences
ICTS-TIFR, Bengaluru

National Centre for Biological Sciences
NCBS-TIFR, Bengaluru

Centre Leadership

Prof. Rajesh Gopakumar
Director, ICTS

Prof. L. S. Shashidhara
Director, NCBS

Donors

Mr. Vishal Gupta
Founder, Reed India Consulting

Major Deepshikha Gupta