Reading Material

ICTP - ICTS Winter School on Quantitative Systems Biology

Reading Material

Maithreyi Narasimha:

Link 1

Link 2

Fernando Casares:

“How the leopard changed its spots”, by Brian Goodwin.

“The plausibility of life”, by Jon Gerhart and Mark Kirschner

Control of size, fate and time by the Hh morphogen in the eyes of flies - Link

Open Biology - Growth and size control during development - Link

Vidyanand Nanjundiah:

*(1) Gilbert S F (2003). The morphogenesis of evolutionary developmental biology. Int. J. Dev. Biol. 47: 467-477 (2003) (http://evolbiol.ru/docs/docs/_chn09.pdf) - LINK

(2) Behera, N. & Nanjundiah, V. (2004). Phenotypic plasticity can potentiate rapid evolutionary change. J. Theor. Biol. 226: 177–184 (2004). - LINK

*(3) Bateson, P (2005). The return of the whole organism. J. Biosci: 30, 31–39. (https://www.ias.ac.in/article/fulltext/jbsc/030/01/0031-0039). - LINK

(4) Abouheif, E., Favé, M.-J., Ibarrarán-Viniegra, A. S., Lesoway, M. P., Rafiqi, A. M., & Rajakumar, R. (2013). Eco-Evo-Devo: The Time Has Come. Ecological Genomics, 107–125. - LINK

*(5) Gilbert S F, Bosch T C G & Ledón-Rettig C (2015).

Eco-Evo-Devo: developmental symbiosis and developmental plasticity as evolutionary agents . Nature Reviews Genetics 16: 611–622. (https://www.nature.com/articles/nrg3982)

(6) Altenberg-phenotypic plasticity_ compressed - LINK

(7) Evolution of multicellularity - Link

Mounia Lagha:

Reading: general review on transcription :

Review Lagha et al., TIGS 2012

Vikas Trivedi:

Monday, 16 December 2019

The evolution of body axes: A synthetic approach

In this lecture we will discuss how conserved signalling pathways in early embryos, which are limited in number, give rise to robust formation of body axes and how did axial patterning emerge over time.

References:

Cells, Embryos and Evolution 1st Edition, Jon Gerhart, Marc Kirschner - Link

Friday, 20 December 2019

Modularity in Biology: Formation of tubular structures

In this lecture we will discuss the concept of modularity and how different morphological processes can result in similar geometrical results.

References:

Modularity in Development and Evolution 1st Edition, Gerhard Schlosser & Günter P. Wagner - Link

Karen Alim:

Purcell E. Life at low Reynolds number. Am J Phys. 1977;45(1):3-11.

Jochen Rink:

Succinct review on planarian biology (background reading, in case someone is curious):

Model systems for regeneration: planarians.

Ivankovic M, Haneckova R, Thommen A, Grohme MA, Vila-Farré M, Werner S, Rink JC.

Development. 2019 Sep 11;146(17). pii: dev167684. doi: 10.1242/dev.167684. Review.

PMID: 31511248

The two papers that I will cover in my talks:

Body size-dependent energy storage causes Kleiber's law scaling of the metabolic rate in planarians.

Thommen A, Werner S, Frank O, Philipp J, Knittelfelder O, Quek Y, Fahmy K, Shevchenko A, Friedrich BM, Jülicher F, Rink JC.

Elife. 2019 Jan 4;8. pii: e38187. doi: 10.7554/eLife.38187.

PMID: 30608231 Free PMC Article

Dynamic Polarization of the Multiciliated Planarian Epidermis between Body Plan Landmarks.

Vu HT, Mansour S, Kücken M, Blasse C, Basquin C, Azimzadeh J, Myers EW, Brusch L, Rink JC.

Dev Cell. 2019 Nov 18;51(4):526-542.e6. doi: 10.1016/j.devcel.2019.10.022.

PMID: 31743666